Signal Words and Toxicity Classes

Core PrincipleIntermediate Level

Understanding DANGER, WARNING, CAUTION signal words indicating acute toxicity levels and associated precautions.

Detailed Overview

EPA assigns toxicity categories based on acute toxicity tests. Signal words required on labels: (1) DANGER - POISON: Category I - Highly toxic. Lethal dose less than 50 mg/kg. Skull and crossbones symbol. May be fatal if swallowed, inhaled, or absorbed through skin. Requires extensive PPE. Used mainly in restricted-use products - fumigants, some rodenticides. PCOs rarely use. (2) WARNING: Category II - Moderately toxic. Lethal dose 50-500 mg/kg. May be harmful if swallowed, inhaled, or absorbed. Requires PPE (usually gloves, eye protection). Many professional insecticides in this category. (3) CAUTION: Category III & IV - Slightly toxic or relatively non-toxic. Lethal dose over 500 mg/kg. Harmful if swallowed, inhaled, or absorbed. Minimum PPE. Most ready-to-use consumer products. Signal word based on most toxic exposure route (oral, dermal, inhalation, eye/skin irritation). Product may have different toxicities by different routes. Toxicity refers to acute (short-term high dose) effects, not chronic (long-term low dose). Chronic effects listed separately. Lower toxicity does not mean safe to misuse - all pesticides require careful handling per label.

When to Use

Check signal word when selecting products. Understand toxicity level. Use appropriate PPE and precautions. Choose lower toxicity products when options available for same pest.

Required Skill Level

Intermediate

Requires some training and experience in pest management

Benefits

  • Quickly identifies product toxicity level
  • Guides appropriate precautions and PPE
  • Helps select safer products when available
  • Standardized system across all pesticides
  • Warns of most hazardous products

Limitations

  • Acute toxicity only - does not reflect chronic effects
  • Does not indicate environmental toxicity
  • Low toxicity to humans may be high to fish/bees
  • Signal word alone does not determine safety

Related Concepts

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Important Disclaimer: The information provided in this knowledge base is for educational and reference purposes only. Pest management professionals should always consult current product labels, Safety Data Sheets (SDS), manufacturer instructions, and applicable local, state, and federal regulations as the definitive source of truth. Product formulations, application methods, safety requirements, and regulations may change over time. This information may be out of date and should not replace professional judgment, proper training, or required licensing and certifications.