Resistance Management

Core PrincipleProfessional Level

Strategies to prevent or delay pest populations from developing resistance to pesticides through product rotation and MoA diversity.

Detailed Overview

Pesticide resistance occurs when repeated use of the same chemistry selects for individuals that survive treatment, eventually creating resistant populations. Bed bugs have developed widespread resistance to pyrethroids. German roaches show resistance to various insecticide classes. The solution: rotate products with different modes of action. Do not rotate between products in the same chemical class (all pyrethroids have same MoA regardless of active ingredient). Use IRAC/RRAC group numbers to identify different MoAs. Establish rotation schedules: use Product A (MoA 3) for 6-12 months, switch to Product B (MoA 4) next period, then Product C (MoA 28). Combine chemistry with non-chemical methods to reduce selection pressure. Use tank mixes of products with different MoAs for high-resistance risk pests. Monitor treatment effectiveness - declining control may signal developing resistance. Desiccant dusts and heat treatments cannot be resisted because they use physical mechanisms. When resistance suspected, switch to different MoA class immediately and increase non-chemical controls.

When to Use

Implement rotation programs for all accounts, especially those requiring frequent treatments. Rotate MoA groups annually minimum. Switch immediately if declining control suggests resistance developing.

Required Skill Level

Professional

Should only be performed by licensed pest management professionals

Benefits

  • Extends useful life of effective products
  • Prevents resistance development in pest populations
  • Maintains treatment effectiveness long-term
  • Reduces callbacks from treatment failures
  • Provides alternative options when resistance occurs

Limitations

  • Requires tracking which products used at each account
  • Limited products available in some MoA classes
  • Costs may vary between products in rotation
  • Resistance may already exist in local populations
  • Requires ongoing education about new products and MoAs

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Important Disclaimer: The information provided in this knowledge base is for educational and reference purposes only. Pest management professionals should always consult current product labels, Safety Data Sheets (SDS), manufacturer instructions, and applicable local, state, and federal regulations as the definitive source of truth. Product formulations, application methods, safety requirements, and regulations may change over time. This information may be out of date and should not replace professional judgment, proper training, or required licensing and certifications.